IRIS  Catalogo Istituzionale della Ricerca dell'Università degli Studi del Molise

Adequate lymphadenectomy and adjuvant capecitabine warrant survival benefit in gallbladder cancer

Background: Significant heterogeneity exists in the management of resectable gallbladder cancer (GBC), regarding the extent of lymphadenectomy and the role of adjuvant chemotherapy (aCTx). This study investigates outcomes of resected GBC according to contemporary surgical oncology principles. Methods: The international database of the GBC Study Group was queried for patients with resected GBC between 2012 and 2022. Patients with ≥6 lymph nodes resected and aCTx were compared to those with ina...

Imaging-based 3D-printed anatomical models for preoperative planning in hepatopancreatobiliary surgery: a single-center pilot study, cost analysis, and systematic review

Patient-specific three-dimensional (3D)-printed models are increasingly used to optimize preoperative planning in complex hepatopancreatobiliary (HPB) surgery. This single-center study evaluated their anatomical accuracy, clinical utility, cost efficiency, and educational value for surgical planning and training. Three patients with complex HPB lesions (pancreatic head adenocarcinoma, ampullary carcinoma, and giant hepatic hemangioma) were selected based on lesion size (> 3 cm) and su...

Explainable and Robust Deep Learning for Liver Segmentation Through U-Net Network

Background/Objectives: Clinical imaging techniques, such as magnetic resonance imaging and computed tomography, play a vital role in supporting clinicians by aiding disease diagnosis and facilitating the planning of appropriate interventions. This is particularly important in malignant conditions like hepatocellular carcinoma, where accurate image segmentation, delineating the liver and tumor, is a critical initial step in optimizing diagnosis, staging, and treatment planning, including inter...

La piattaforma digitale come "organizzazione del mercato": nuove prospettive in tema di subordinazione