Amphiphilic poly(ethylene oxide) - poly(propylene oxide) triblock copolymers are very appealing materials for biomedical application since they can be easily injected as liquid at room temperature while they produce a gel when in the body. on the other hand, these materials no longer hold the gel state when in presence of solvent (as physiological solutions) due to the dilution of the system. To overcome these limitations Cohn and coworkers([1]) have synthesized a novel thermoresponsive systems by extending the chain of the commercially available PEO-PPO copolymer named F127. The aim of this study was to evaluate the effect of the chemical modification on the macroscopic, rheological, and microscopic, transport, properties of these new materials.
Micro and macro characterization of PEO-PPO-PEO triblocks hydrogels
Fusco S
;
2008-01-01
Abstract
Amphiphilic poly(ethylene oxide) - poly(propylene oxide) triblock copolymers are very appealing materials for biomedical application since they can be easily injected as liquid at room temperature while they produce a gel when in the body. on the other hand, these materials no longer hold the gel state when in presence of solvent (as physiological solutions) due to the dilution of the system. To overcome these limitations Cohn and coworkers([1]) have synthesized a novel thermoresponsive systems by extending the chain of the commercially available PEO-PPO copolymer named F127. The aim of this study was to evaluate the effect of the chemical modification on the macroscopic, rheological, and microscopic, transport, properties of these new materials.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
