Introduction: Intravitreal anti-VEGF is the most effective therapy for wet AMD, although systemic effects on the endothelium cannot be excluded. Areas covered: The purpose of this review was to evaluate risk of thromboembolic events associated with intravitreal anti-VEGF. Expert opinion: Current data are insufficient to confirm the safety of these compounds, due to the paucity of specific studies. Thus, pharmacovigilance for all anti-VEGF should be improved to verify the true role of anti-VEGF in the occurrence of systemic adverse events.
|Digital Object Identifier (DOI):||10.1080/14740338.2019.1643838|
|Codice identificativo ISI:||WOS:000477515400001|
|Codice identificativo Scopus:||2-s2.0-85071045119|
|Titolo:||Systemic thromboembolic adverse events in patients treated with intravitreal anti-VEGF drugs for neovascular age-related macular degeneration: an update|
|Appare nelle tipologie:||1.1 Articolo in rivista|