Mycosis fungoides (MF) is the major subtype of cutaneous T-cell lymphomas (CTCL). It usually has a prolonged indolent clinical course with a minority of cases acquiring a more aggressive biological profile and resistance to conventional therapies, partially attributed to the persistent activation of Nuclear Factor-kappa B (NF-κB) pathway. In the last decade, several papers suggested an important role for the FK506-binding protein 51 (FKBP51), an immunophilin initially cloned in lymphocytes, in the control of NF-κB pathway in different types of human malignancies.
|Digital Object Identifier (DOI):||10.1111/jdv.14614|
|Codice identificativo ISI:||WOS:000430468700040|
|Codice identificativo Scopus:||2-s2.0-85045769371|
|Titolo:||Expression of FK506-binding protein 51 (FKBP51) in Mycosis Fungoides|
|Appare nelle tipologie:||1.1 Articolo in rivista|