Brain abscesses are a rare, severe complication of orthotopic liver t nsplantation (OLT).They are almost exclusively due to fungi, Nocardia, orToxoplasma, and usually occur within months of surgery. Here we report the case of an adolescent who developed a brain abscess due to Klebsiella pneumoniae 11.5 years after OLT. Fever was absent and laboratory parameters were not indicative of infectious disease, and therefore the diagnosis of a central nervous system neoplasm was considered. Subsequent magnetic resonance imaging and spectroscopy led to a diagnosis of a brain abscess, and to prompt appropriate antibiotic treatment.This case shows that K. pneumoniae may cause a brain abscess long after liver transplantation.The appearance of neurological symptoms should alert clinicians to consider a brain abscess even in the absence of overt clinical/laboratory signs of in£ammation, which may be blunted by chronic immunosuppression.
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1111/j.1399-3062.2009.00395.x|
|Codice identificativo ISI:||WOS:000268714600011|
|Codice identificativo Scopus:||2-s2.0-68849088161|
|Titolo:||Brain abscess due to Klebsiella pneumoniae in a liver-transplanted child|
|Appare nelle tipologie:||1.1 Articolo in rivista|