Perivascular epithelioid cell tumors (PEComas) are a family of rare mesenchymal neoplasms, including angiomyolipoma, clear-cell "sugar" tumor of the lung and extrapulmonary sites, lymphangioleiomyomatosis, clear-cell myomelanocytic tumor of the falciform ligament/ligamentum teres, and clear-cell tumors at various other anatomic sites. These tumors are characterized by a proliferation of epithelioid cells with clear to eosinophilic cytoplasm, perivascular distribution, and coexpression of myogenic and melanocytic markers. PEComas show a female predominance, occur with some frequency in the gynecological tract, and have an unpredictable biological behavior. We report a case of a huge malignant PEComa arising from the uterine cervix and vagina. To the best of our knowledge, only 6 cases of PEComa in the cervix and 2 cases in the vagina have been reported in the literature. (C) 2013 Elsevier GmbH. All rights reserved.
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.prp.2013.10.003|
|Codice identificativo ISI:||WOS:000332428600009|
|Codice identificativo Scopus:||2-s2.0-84893723811|
|Titolo:||A huge malignant perivascular epithelioid cell tumor (PEComa) of the uterine cervix and vagina|
|Appare nelle tipologie:||1.1 Articolo in rivista|