The present investigation has been performed to obtain a complete distributional map of the oligosaccharidic component of the glycoconjugates in the testis of the human newborn. For this purpose seven eight HRP-conjugated lectins (SBA, DBA, PNA, WGA, OOA, UEAI, LTA and ConA) along with enzymatic treatments, were used. The Sertoli cells were characterized by the same sugar residues detected in the testes of adult healthy subject. β-N-acetyl-D- galactosamine in the Leydig's cells and α-N- acetyl-D-galactosamine anomer in the spermatogonia seem to be an unique feature of the newborn testis. For this fact SBA and DBA could be considered markers respectively of the Leydig's cells and of the spermatogonia in the newborn testis. Differences in lectin binding, between the newborn and the adult testis as the interstitial tissue and the endothelial cells of the capillary vessels are reported.

Lectin-binding sites in newborn human testis

SGAMBATI, Eleonora
2004-01-01

Abstract

The present investigation has been performed to obtain a complete distributional map of the oligosaccharidic component of the glycoconjugates in the testis of the human newborn. For this purpose seven eight HRP-conjugated lectins (SBA, DBA, PNA, WGA, OOA, UEAI, LTA and ConA) along with enzymatic treatments, were used. The Sertoli cells were characterized by the same sugar residues detected in the testes of adult healthy subject. β-N-acetyl-D- galactosamine in the Leydig's cells and α-N- acetyl-D-galactosamine anomer in the spermatogonia seem to be an unique feature of the newborn testis. For this fact SBA and DBA could be considered markers respectively of the Leydig's cells and of the spermatogonia in the newborn testis. Differences in lectin binding, between the newborn and the adult testis as the interstitial tissue and the endothelial cells of the capillary vessels are reported.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11695/3303
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