The observation of neurological dysfunctions resembling multiple sclerosis (MS) seen clinically and/or by MRI in patients with celiac disease has focused attention on the possibility that cryptic gluten sensitivity may be involved in the pathogenesis of MS. Here we study the effects of a gluten-free diet on the course of protracted-relapsing EAE in DA rats, serving as a preclinical model of human MS. The data show not only that this nutritional approach failed to ameliorate development of the disease but rather that it exacerbated the course.
|Digital Object Identifier (DOI):||10.1111/j.1600-0463.2004.apm1121003.x|
|Codice identificativo ISI:||000226245700003|
|Codice identificativo Scopus:||2-s2.0-11944258343|
|Appare nelle tipologie:||1.1 Articolo in rivista|