We investigated an outbreak of Serratia marcescens in the adult intensive care unit of the University Hospital of Napoli. The outbreak involved 13 cases of infection by S. marcescens over a nine-month period and was caused by a single pulsed-field gel electrophoresis clone. The epidemic strain was multiply antibiotic resistant, producing an inducible Amp C-type beta-lactamase enzyme and carrying the trimethoprim-resistance gene and the adenyltransferase gene, which confers resistance to streptomycin and spectinomycin, within a class 1 integron. Antimicrobial therapy with beta-lactams was associated with S. marcescens acquisition in the intensive care unit. © 2003 The Hospital Infection Society. Published by Elsevier Ltd. All rights reserved.
|Digital Object Identifier (DOI):||10.1016/j.jhin.2003.07.004|
|Codice identificativo ISI:||000188163900006|
|Codice identificativo Scopus:||2-s2.0-0348229014|
|Appare nelle tipologie:||1.1 Articolo in rivista|