The site of Isernia La Pineta is characterised by the presence of several anthropic layers set within a complex stratigraphic sequence. The highest concentration of palaeontological and palaeoethnological finds is documented on archaeosurface 3a, which has so far been explored over an area of several hundred metres. In order to develop the investigations concerning the processes and stages of its formation, a context of intra-site spatial analyses has been applied, using a GIS application. In the specific case of Isernia La Pineta, this application has also encouraged experimentation with new computerised documentation techniques.