CHINI, Maria Giovanna
CHINI, Maria Giovanna
DIPARTIMENTO DI BIOSCIENZE E TERRITORIO
2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines
2023-01-01 De Vita, Simona; Meninno, Sara; Capasso, Lucia; Colarusso, Ester; Chini, Maria Giovanna; Lauro, Gianluigi; Rinaldi, Romolo; De Cicco, Annalisa; Sian, Veronica; Terracciano, Stefania; Nebbioso, Angela; Lattanzi, Alessandra; Bifulco, Giuseppe
4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity
2012-01-01 De Marino, Simona; Ummarino, Raffaella; Valeria D’Auria, Maria; Chini, Maria Giovanna; Bifulco, Giuseppe; D’Amore, Claudio; Renga, Barbara; Mencarelli, Andrea; Petek, Sylvain; Fiorucci, Stefano; Zampella, Angela
6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis
2022-01-01 Colarusso, E; Gazzillo, E; Boccia, E; Giordano, A; Chini, Mg; Bifulco, G; Lauro, G
A Chemical-Biological Study Reveals C-9-type Iridoids as Novel Heat Shock Protein 90 (Hsp90) Inhibitors
2013-01-01 Dal Piaz, F.; Vassallo, A.; Temraz, A.; Cotugno, R.; Belisario, M. A .; Bifulco, G.; Chini, M. G.; Pisano, C.; De Tommasi, N.; Braca, A.
A Novel Potent Nicotinamide Phosphoribosyltransferase Inhibitor Synthesized via Click Chemistry
2010-01-01 G., Colombano; C., Travelli; U., Galli; A., Caldarelli; Chini, MARIA GIOVANNA; P. L., Canonico; G., Sorba; Bifulco, Giuseppe; G. C., Tron; A. A., Genazzani
Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19)
2020-01-01 De Vita, S.; Chini, M. G.; Lauro, G.; Bifulco, G.
Addressing the Target Identification and Accelerating the Repositioning of Anti-Inflammatory/Anti-Cancer Organic Compounds by Computational Approaches
2021-01-01 Chini, M. G.; Lauro, G.; Bifulco, G.
Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions
2017-01-01 Maione, Francesco; Cantone, Vincenza; Pace, Simona; Chini, Maria Giovanna; Bisio, Angela; Romussi, Giovanni; Pieretti, Stefano; Werz, Oliver; Koeberle, Andreas; Mascolo, Nicola; Bifulco, Giuseppe
Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests
2021-01-01 De Vita, Simona; Chini, Maria Giovanna; Saviano, Gabriella; Finamore, Claudia; Festa, Carmen; Lauro, Gianluigi; De Marino, Simona; Russo, Roberto; Avagliano, Carmen; Casapullo, Agostino; Calignano, Antonio; Bifulco, Giuseppe; Iorizzi, Maria
Can Small Chemical Modifications of Natural Pan-inhibitors Modulate the Biological Selectivity? the Case of Curcumin Prenylated Derivatives Acting as HDAC or mPGES-1 Inhibitors
2015-01-01 Iranshahi, Mehrdad; Chini, MARIA GIOVANNA; Masullo, Milena; Sahebkar, Amirhossein; Javidnia, Azita; Chitsazian Yazdi, Mahsa; Pergola, Carlo; Koeberle, Andreas; Werz, Oliver; Pizza, Cosimo; Terracciano, Stefania; Piacente, Sonia; Bifulco, Giuseppe
Carnosol Attenuates LPS-Induced Inflammation of Cardiomyoblasts by Inhibiting NF-κB: A Mechanistic in Vitro and in Silico Study
2022-01-01 Baradaran Rahimi, Vafa; Momeni-Moghaddam, Mohammad Amin; Chini, Maria Giovanna; Saviano, Anella; Maione, Francesco; Bifulco, Giuseppe; Rahmanian-Devin, Pouria; Jebalbarezy, Ali; Askari, Vahid Reza
Chemical Profiling of Polar Lipids and the Polyphenolic Fraction of Commercial Italian Phaseolus Seeds by UHPLC-HRMS and Biological Evaluation
2024-01-01 Samukha, Vadym; Fantasma, Francesca; D'Urso, Gilda; Colarusso, Ester; Schettino, Anna; Marigliano, Noemi; Chini, Maria Giovanna; Saviano, Gabriella; De Felice, Vincenzo; Lauro, Gianluigi; Maione, Francesco; Bifulco, Giuseppe; Casapullo, Agostino; Iorizzi, Maria
Chemoproteomics Reveals USP5 (Ubiquitin Carboxyl-Terminal Hydrolase 5) as Promising Target of the Marine Polyketide Gracilioether A
2024-01-01 Capuano, Alessandra; D’Urso, Gilda; Aliberti, Michela; Ruggiero, Dafne; Terracciano, Stefania; Festa, Carmen; Tosco, Alessandra; Chini, Maria Giovanna; Lauro, Gianluigi; Bifulco, Giuseppe; Casapullo, Agostino
Computational NMR Methods in the Stereochemical Analysis of Organic Compounds: Are Proton or Carbon NMR Chemical Shift Data More Discriminating?
2015-01-01 Chini, MARIA GIOVANNA; Riccio, Raffaele; Bifulco, Giuseppe
Conformationally locked calixarene-based histone deacetylase inhibitors
2010-01-01 Chini, M. G.; Terracciano, S.; Riccio, R.; Bifulco, G.; Ciao, R.; Gaeta, C.; Troisi, F.; Neri, P.
Conicasterol E, a Small Heterodimer Partner Sparing Farnesoid X Receptor Modulator Endowed with a Pregnane X Receptor Agonistic Activity, from the Marine SpongeTheonella swinhoei
2012-01-01 Sepe, Valentina; Ummarino, Raffaella; Valeria D’Auria, Maria; Chini, Maria Giovanna; Bifulco, Giuseppe; Renga, Barbara; D’Amore, Claudio; Debitus, Cécile; Fiorucci, Stefano; Zampella, Angela
Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors
2016-01-01 Terracciano, Stefania; Chini, Maria Giovanna; Vaccaro, Mariacarmela; Strocchia, Maria; Foglia, Antonio; Vassallo, Antonio; Saturnino, Carmela; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines
Cytotoxic Sesquiterpenoids from Ammoides atlantica Aerial Parts
2021-01-01 Boudermine, S.; Parisi, V.; Lemoui, R.; Boudiar, T.; Chini, M. G.; Franceschelli, S.; Pecoraro, M.; Pascale, M.; Bifulco, G.; Braca, A.; De Tommasi, N.; De Leo, M.
Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors
2012-01-01 Chini, Maria Giovanna; De Simone, Rosa; Bruno, Ines; Riccio, Raffaele; Dehm, Friederike; Weinigel, Christina; Barz, Dagmar; Werz, Oliver; Bifulco, Giuseppe
Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors
2012-01-01 Terracciano, Stefania; Chini, Maria Giovanna; Riccio, Raffaele; Bruno, Ines; Bifulco, Giuseppe
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines | 1-gen-2023 | De Vita, Simona; Meninno, Sara; Capasso, Lucia; Colarusso, Ester; Chini, Maria Giovanna; Lauro, Gianluigi; Rinaldi, Romolo; De Cicco, Annalisa; Sian, Veronica; Terracciano, Stefania; Nebbioso, Angela; Lattanzi, Alessandra; Bifulco, Giuseppe | |
| 4-Methylenesterols from Theonella swinhoei sponge are natural pregnane-X-receptor agonists and farnesoid-X-receptor antagonists that modulate innate immunity | 1-gen-2012 | De Marino, Simona; Ummarino, Raffaella; Valeria D’Auria, Maria; Chini, Maria Giovanna; Bifulco, Giuseppe; D’Amore, Claudio; Renga, Barbara; Mencarelli, Andrea; Petek, Sylvain; Fiorucci, Stefano; Zampella, Angela | |
| 6-Methylquinazolin-4(3H)-one Based Compounds as BRD9 Epigenetic Reader Binders: A Rational Combination of in silico Studies and Chemical Synthesis | 1-gen-2022 | Colarusso, E; Gazzillo, E; Boccia, E; Giordano, A; Chini, Mg; Bifulco, G; Lauro, G | |
| A Chemical-Biological Study Reveals C-9-type Iridoids as Novel Heat Shock Protein 90 (Hsp90) Inhibitors | 1-gen-2013 | Dal Piaz, F.; Vassallo, A.; Temraz, A.; Cotugno, R.; Belisario, M. A .; Bifulco, G.; Chini, M. G.; Pisano, C.; De Tommasi, N.; Braca, A. | |
| A Novel Potent Nicotinamide Phosphoribosyltransferase Inhibitor Synthesized via Click Chemistry | 1-gen-2010 | G., Colombano; C., Travelli; U., Galli; A., Caldarelli; Chini, MARIA GIOVANNA; P. L., Canonico; G., Sorba; Bifulco, Giuseppe; G. C., Tron; A. A., Genazzani | |
| Accelerating the repurposing of FDA-approved drugs against coronavirus disease-19 (COVID-19) | 1-gen-2020 | De Vita, S.; Chini, M. G.; Lauro, G.; Bifulco, G. | |
| Addressing the Target Identification and Accelerating the Repositioning of Anti-Inflammatory/Anti-Cancer Organic Compounds by Computational Approaches | 1-gen-2021 | Chini, M. G.; Lauro, G.; Bifulco, G. | |
| Anti-inflammatory and analgesic activity of carnosol and carnosic acid in vivo and in vitro and in silico analysis of their target interactions | 1-gen-2017 | Maione, Francesco; Cantone, Vincenza; Pace, Simona; Chini, Maria Giovanna; Bisio, Angela; Romussi, Giovanni; Pieretti, Stefano; Werz, Oliver; Koeberle, Andreas; Mascolo, Nicola; Bifulco, Giuseppe | |
| Biological Profile of Two Gentiana lutea L. Metabolites Using Computational Approaches and In Vitro Tests | 1-gen-2021 | De Vita, Simona; Chini, Maria Giovanna; Saviano, Gabriella; Finamore, Claudia; Festa, Carmen; Lauro, Gianluigi; De Marino, Simona; Russo, Roberto; Avagliano, Carmen; Casapullo, Agostino; Calignano, Antonio; Bifulco, Giuseppe; Iorizzi, Maria | |
| Can Small Chemical Modifications of Natural Pan-inhibitors Modulate the Biological Selectivity? the Case of Curcumin Prenylated Derivatives Acting as HDAC or mPGES-1 Inhibitors | 1-gen-2015 | Iranshahi, Mehrdad; Chini, MARIA GIOVANNA; Masullo, Milena; Sahebkar, Amirhossein; Javidnia, Azita; Chitsazian Yazdi, Mahsa; Pergola, Carlo; Koeberle, Andreas; Werz, Oliver; Pizza, Cosimo; Terracciano, Stefania; Piacente, Sonia; Bifulco, Giuseppe | |
| Carnosol Attenuates LPS-Induced Inflammation of Cardiomyoblasts by Inhibiting NF-κB: A Mechanistic in Vitro and in Silico Study | 1-gen-2022 | Baradaran Rahimi, Vafa; Momeni-Moghaddam, Mohammad Amin; Chini, Maria Giovanna; Saviano, Anella; Maione, Francesco; Bifulco, Giuseppe; Rahmanian-Devin, Pouria; Jebalbarezy, Ali; Askari, Vahid Reza | |
| Chemical Profiling of Polar Lipids and the Polyphenolic Fraction of Commercial Italian Phaseolus Seeds by UHPLC-HRMS and Biological Evaluation | 1-gen-2024 | Samukha, Vadym; Fantasma, Francesca; D'Urso, Gilda; Colarusso, Ester; Schettino, Anna; Marigliano, Noemi; Chini, Maria Giovanna; Saviano, Gabriella; De Felice, Vincenzo; Lauro, Gianluigi; Maione, Francesco; Bifulco, Giuseppe; Casapullo, Agostino; Iorizzi, Maria | |
| Chemoproteomics Reveals USP5 (Ubiquitin Carboxyl-Terminal Hydrolase 5) as Promising Target of the Marine Polyketide Gracilioether A | 1-gen-2024 | Capuano, Alessandra; D’Urso, Gilda; Aliberti, Michela; Ruggiero, Dafne; Terracciano, Stefania; Festa, Carmen; Tosco, Alessandra; Chini, Maria Giovanna; Lauro, Gianluigi; Bifulco, Giuseppe; Casapullo, Agostino | |
| Computational NMR Methods in the Stereochemical Analysis of Organic Compounds: Are Proton or Carbon NMR Chemical Shift Data More Discriminating? | 1-gen-2015 | Chini, MARIA GIOVANNA; Riccio, Raffaele; Bifulco, Giuseppe | |
| Conformationally locked calixarene-based histone deacetylase inhibitors | 1-gen-2010 | Chini, M. G.; Terracciano, S.; Riccio, R.; Bifulco, G.; Ciao, R.; Gaeta, C.; Troisi, F.; Neri, P. | |
| Conicasterol E, a Small Heterodimer Partner Sparing Farnesoid X Receptor Modulator Endowed with a Pregnane X Receptor Agonistic Activity, from the Marine SpongeTheonella swinhoei | 1-gen-2012 | Sepe, Valentina; Ummarino, Raffaella; Valeria D’Auria, Maria; Chini, Maria Giovanna; Bifulco, Giuseppe; Renga, Barbara; D’Amore, Claudio; Debitus, Cécile; Fiorucci, Stefano; Zampella, Angela | |
| Correction: Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors | 1-gen-2016 | Terracciano, Stefania; Chini, Maria Giovanna; Vaccaro, Mariacarmela; Strocchia, Maria; Foglia, Antonio; Vassallo, Antonio; Saturnino, Carmela; Riccio, Raffaele; Bifulco, Giuseppe; Bruno, Ines | |
| Cytotoxic Sesquiterpenoids from Ammoides atlantica Aerial Parts | 1-gen-2021 | Boudermine, S.; Parisi, V.; Lemoui, R.; Boudiar, T.; Chini, M. G.; Franceschelli, S.; Pecoraro, M.; Pascale, M.; Bifulco, G.; Braca, A.; De Tommasi, N.; De Leo, M. | |
| Design and synthesis of a second series of triazole-based compounds as potent dual mPGES-1 and 5-lipoxygenase inhibitors | 1-gen-2012 | Chini, Maria Giovanna; De Simone, Rosa; Bruno, Ines; Riccio, Raffaele; Dehm, Friederike; Weinigel, Christina; Barz, Dagmar; Werz, Oliver; Bifulco, Giuseppe | |
| Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors | 1-gen-2012 | Terracciano, Stefania; Chini, Maria Giovanna; Riccio, Raffaele; Bruno, Ines; Bifulco, Giuseppe |