AMBROSINO, Paolo
AMBROSINO, Paolo
DIPARTIMENTO DI MEDICINA E DI SCIENZE DELLA SALUTE
A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy
2019-01-01 Lauritano, A.; Moutton, S.; Longobardi, E.; Tran Mau-Them, F.; Laudati, G.; Nappi, P.; Soldovieri, M. V.; Ambrosino, P.; Cataldi, M.; Jouan, T.; Lehalle, D.; Maurey, H.; Philippe, C.; Miceli, F.; Vitobello, A.; Taglialatela, M.
A novel KCNC1 gain-of-function variant causing developmental and epileptic encephalopathy: "Precision medicine" approach with fluoxetine
2023-01-01 Ambrosino, Paolo; Ragona, Francesca; Mosca, Ilaria; Vannicola, Chiara; Canafoglia, Laura; Solazzi, Roberta; Rivolta, Ilaria; Freri, Elena; Granata, Tiziana; Messina, Giuliana; Castellotti, Barbara; Gellera, Cinzia; Soldovieri, Maria Virginia; Difrancesco, Jacopo Cosimo; Taglialatela, Maurizio
Activation of Kv7 potassium channels inhibits intracellular Ca2+ increases triggered by TRPV1-mediated pain-inducing stimuli in F11 immortalized sensory neurons
2019-01-01 Ambrosino, P.; Soldovieri, M. V.; Di Zazzo, E.; Paventi, G.; Iannotti, F. A.; Mosca, I.; Miceli, F.; Franco, C.; Canzoniero, L. M. T.; Taglialatela, M.
Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors
2020-01-01 Alaimo, A.; Lorenzoni, M.; Ambrosino, P.; Bertossi, A.; Bisio, A.; Macchia, A.; Zoni, E.; Genovesi, S.; Cambuli, F.; Foletto, V.; De Felice, D.; Soldovieri, M. V.; Mosca, I.; Gandolfi, F.; Brunelli, M.; Petris, G.; Cereseto, A.; Villarroel, A.; Thalmann, G.; Carbone, F. G.; Kruithof-de Julio, M.; Barbareschi, M.; Romanel, A.; Taglialatela, M.; Lunardi, A.
Characterization of two de novo KCNT1 mutations in children with malignant migrating partial seizures in infancy
2016-01-01 Rizzo, F; Ambrosino, P; Guacci, A; Chetta, M; Marchese, G; Rocco, T; Soldovieri, Mv; Manocchio, L; Mosca, I; Casara, G; Vecchi, Paolo Maria; Taglialatela, M; Coppola, G; Weisz, A
De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy
2018-01-01 Ambrosino, Paolo; Soldovieri, Maria Virginia; Bast, Thomas; Turnpenny, Peter D.; Uhrig, Sabine; Biskup, Saskia; Döcker, Miriam; Fleck, Thilo; Mosca, Ilaria; Manocchio, Laura; Iraci, Nunzio; Taglialatela, Maurizio; Lemke, Johannes R.
De novo variants in KCNA3 cause developmental and epileptic encephalopathy
2024-01-01 Soldovieri, Maria Virginia; Ambrosino, Paolo; Mosca, Ilaria; Servettini, Ilenio; Pietrunti, Francesca; Belperio, Giorgio; Syrbe, Steffen; Taglialatela, Maurizio; Lemke, Johannes R
Differential Regulation of PI(4,5)P2Sensitivity of Kv7.2 and Kv7.3 Channels by Calmodulin
2017-01-01 Gomis-Perez, Carolina; Soldovieri, Maria V; Malo, Covadonga; Ambrosino, Paolo; Taglialatela, Maurizio; Areso, Pilar; Villarroel, Alvaro
Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy
2018-01-01 Dilena, Robertino; Difrancesco, Jacopo C.; Soldovieri, Maria Virginia; Giacobbe, Antonella; Ambrosino, Paolo; Mosca, Ilaria; Galli, Maria Albina; Guez, Sophie; Fumagalli, Monica; Miceli, Francesco; Cattaneo, Dario; Darra, Francesca; Gennaro, Elena; Zara, Federico; Striano, Pasquale; Castellotti, Barbara; Gellera, Cinzia; Varesio, Costanza; Veggiotti, Pierangelo; Taglialatela, Maurizio
Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate
2016-01-01 Soldovieri, Maria Virginia; Ambrosino, Paolo; Mosca, Ilaria; De Maria, M; Moretto, E; Miceli, F; Alaimo, A; Iraci, N; Manocchio, L; Medoro, Alessandro; Passafaro, M; Taglialatela, Maurizio
Early-Onset Epileptic Encephalopathy Caused by Gain-of-Function Mutations in the Voltage Sensor of Kv7.2 and Kv7.3 Potassium Channel Subunits.
2015-01-01 Miceli, F; Soldovieri, Maria Virginia; Ambrosino, Paolo; De Maria, Michela; Migliore, M; Migliore, R; Taglialatela, Maurizio
Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels
2017-01-01 Di Cesare Mannelli, Lorenzo; Lucarini, Elena; Micheli, Laura; Mosca, Ilaria; Ambrosino, Paolo; Soldovieri, Maria Virginia; Martelli, Alma; Testai, Lara; Taglialatela, Maurizio; Calderone, Vincenzo; Ghelardini, Carla
Epilepsy-causing mutations in kv7.2 c-terminus affect binding and functional modulation by calmodulin.
2015-01-01 Ambrosino, Paolo; Alaimo, A; Bartollino, Silvia; Manocchio, Laura; De Maria, Michela; Mosca, Ilaria; Gomis Perez, C; Alberdi, A; Scambia, G; Lesca, G; Villarroel, A; Taglialatela, Maurizio; Soldovieri, Maria Virginia
Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction
2020-01-01 Nappi, P.; Miceli, F.; Soldovieri, M. V.; Ambrosino, P.; Barrese, V.; Taglialatela, M.
Epileptic encephalopathy in a patientwith a novel variant in the Kv7.2 S2 transmembrane segment: Clinical, genetic, and functional features
2019-01-01 Soldovieri, M. V.; Ambrosino, P.; Mosca, I.; Miceli, F.; Franco, C.; Canzoniero, L. M. T.; Kline-Fath, B.; Cooper, E. C.; Venkatesan, C.; Taglialatela, M.
Erratum to: Towards the realization of label-free biosensors through impedance spectroscopy integrated with IDES technology
2012-01-01 Di Capua, R.; Barra, M.; Santoro, F.; Viggiano, D.; Ambrosino, P.; Soldovieri, M. V.; Taglialatela, M.; Cassinese, A.
Expression and function of Kv7.4 channels in Rat cardiac mitochondria: possible targets for cardioprotection
2016-01-01 Testai, L; Barrese, V; Soldovieri, Maria Virginia; Ambrosino, Paolo; Martelli, A; Vinciguerra, I; Miceli, F; Greenwood, I; Curtis, Mj; Breschi, Mc; Sisalli, Mj; Scorziello, A; Canduela, Mj; Grandes, P; Calderone, V; Taglialatela, Maurizio
Functional Characterization of Two Variants at the Intron 6-Exon 7 Boundary of the KCNQ2 Potassium Channel Gene Causing Distinct Epileptic Phenotypes
2022-01-01 Mosca, Ilaria; Rivolta, Ilaria; Labalme, Audrey; Ambrosino, Paolo; Castellotti, Barbara; Gellera, Cinzia; Granata, Tiziana; Freri, Elena; Binda, Anna; Lesca, Gaetan; Difrancesco, Jacopo C; Soldovieri, Maria Virginia; Taglialatela, Maurizio
Gabapentin treatment in a patient with KCNQ2 developmental epileptic encephalopathy
2020-01-01 Soldovieri, M. V.; Freri, E.; Ambrosino, P.; Rivolta, I.; Mosca, I.; Binda, A.; Murano, C.; Ragona, F.; Canafoglia, L.; Vannicola, C.; Solazzi, R.; Granata, T.; Castellotti, B.; Messina, G.; Gellera, C.; Labalme, A.; Lesca, G.; Difrancesco, J. C.; Taglialatela, M.
Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy
2022-01-01 Nappi, Mario; Barrese, Vincenzo; Carotenuto, Lidia; Lesca, Gaetan; Labalme, Audrey; Ville, Dorothee; Smol, Thomas; Rama, Mélanie; Dieux-Coeslier, Anne; Rivier-Ringenbach, Clotilde; Soldovieri, Maria Virginia; Ambrosino, Paolo; Mosca, Ilaria; Pusch, Michael; Miceli, Francesco; Taglialatela, Maurizio
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| A novel homozygous KCNQ3 loss-of-function variant causes non-syndromic intellectual disability and neonatal-onset pharmacodependent epilepsy | 1-gen-2019 | Lauritano, A.; Moutton, S.; Longobardi, E.; Tran Mau-Them, F.; Laudati, G.; Nappi, P.; Soldovieri, M. V.; Ambrosino, P.; Cataldi, M.; Jouan, T.; Lehalle, D.; Maurey, H.; Philippe, C.; Miceli, F.; Vitobello, A.; Taglialatela, M. | |
| A novel KCNC1 gain-of-function variant causing developmental and epileptic encephalopathy: "Precision medicine" approach with fluoxetine | 1-gen-2023 | Ambrosino, Paolo; Ragona, Francesca; Mosca, Ilaria; Vannicola, Chiara; Canafoglia, Laura; Solazzi, Roberta; Rivolta, Ilaria; Freri, Elena; Granata, Tiziana; Messina, Giuliana; Castellotti, Barbara; Gellera, Cinzia; Soldovieri, Maria Virginia; Difrancesco, Jacopo Cosimo; Taglialatela, Maurizio | |
| Activation of Kv7 potassium channels inhibits intracellular Ca2+ increases triggered by TRPV1-mediated pain-inducing stimuli in F11 immortalized sensory neurons | 1-gen-2019 | Ambrosino, P.; Soldovieri, M. V.; Di Zazzo, E.; Paventi, G.; Iannotti, F. A.; Mosca, I.; Miceli, F.; Franco, C.; Canzoniero, L. M. T.; Taglialatela, M. | |
| Calcium cytotoxicity sensitizes prostate cancer cells to standard-of-care treatments for locally advanced tumors | 1-gen-2020 | Alaimo, A.; Lorenzoni, M.; Ambrosino, P.; Bertossi, A.; Bisio, A.; Macchia, A.; Zoni, E.; Genovesi, S.; Cambuli, F.; Foletto, V.; De Felice, D.; Soldovieri, M. V.; Mosca, I.; Gandolfi, F.; Brunelli, M.; Petris, G.; Cereseto, A.; Villarroel, A.; Thalmann, G.; Carbone, F. G.; Kruithof-de Julio, M.; Barbareschi, M.; Romanel, A.; Taglialatela, M.; Lunardi, A. | |
| Characterization of two de novo KCNT1 mutations in children with malignant migrating partial seizures in infancy | 1-gen-2016 | Rizzo, F; Ambrosino, P; Guacci, A; Chetta, M; Marchese, G; Rocco, T; Soldovieri, Mv; Manocchio, L; Mosca, I; Casara, G; Vecchi, Paolo Maria; Taglialatela, M; Coppola, G; Weisz, A | |
| De novo gain-of-function variants in KCNT2 as a novel cause of developmental and epileptic encephalopathy | 1-gen-2018 | Ambrosino, Paolo; Soldovieri, Maria Virginia; Bast, Thomas; Turnpenny, Peter D.; Uhrig, Sabine; Biskup, Saskia; Döcker, Miriam; Fleck, Thilo; Mosca, Ilaria; Manocchio, Laura; Iraci, Nunzio; Taglialatela, Maurizio; Lemke, Johannes R. | |
| De novo variants in KCNA3 cause developmental and epileptic encephalopathy | 1-gen-2024 | Soldovieri, Maria Virginia; Ambrosino, Paolo; Mosca, Ilaria; Servettini, Ilenio; Pietrunti, Francesca; Belperio, Giorgio; Syrbe, Steffen; Taglialatela, Maurizio; Lemke, Johannes R | |
| Differential Regulation of PI(4,5)P2Sensitivity of Kv7.2 and Kv7.3 Channels by Calmodulin | 1-gen-2017 | Gomis-Perez, Carolina; Soldovieri, Maria V; Malo, Covadonga; Ambrosino, Paolo; Taglialatela, Maurizio; Areso, Pilar; Villarroel, Alvaro | |
| Early Treatment with Quinidine in 2 Patients with Epilepsy of Infancy with Migrating Focal Seizures (EIMFS) Due to Gain-of-Function KCNT1 Mutations: Functional Studies, Clinical Responses, and Critical Issues for Personalized Therapy | 1-gen-2018 | Dilena, Robertino; Difrancesco, Jacopo C.; Soldovieri, Maria Virginia; Giacobbe, Antonella; Ambrosino, Paolo; Mosca, Ilaria; Galli, Maria Albina; Guez, Sophie; Fumagalli, Monica; Miceli, Francesco; Cattaneo, Dario; Darra, Francesca; Gennaro, Elena; Zara, Federico; Striano, Pasquale; Castellotti, Barbara; Gellera, Cinzia; Varesio, Costanza; Veggiotti, Pierangelo; Taglialatela, Maurizio | |
| Early-onset epileptic encephalopathy caused by a reduced sensitivity of Kv7.2 potassium channels to phosphatidylinositol 4,5-bisphosphate | 1-gen-2016 | Soldovieri, Maria Virginia; Ambrosino, Paolo; Mosca, Ilaria; De Maria, M; Moretto, E; Miceli, F; Alaimo, A; Iraci, N; Manocchio, L; Medoro, Alessandro; Passafaro, M; Taglialatela, Maurizio | |
| Early-Onset Epileptic Encephalopathy Caused by Gain-of-Function Mutations in the Voltage Sensor of Kv7.2 and Kv7.3 Potassium Channel Subunits. | 1-gen-2015 | Miceli, F; Soldovieri, Maria Virginia; Ambrosino, Paolo; De Maria, Michela; Migliore, M; Migliore, R; Taglialatela, Maurizio | |
| Effects of natural and synthetic isothiocyanate-based H2S-releasers against chemotherapy-induced neuropathic pain: Role of Kv7 potassium channels | 1-gen-2017 | Di Cesare Mannelli, Lorenzo; Lucarini, Elena; Micheli, Laura; Mosca, Ilaria; Ambrosino, Paolo; Soldovieri, Maria Virginia; Martelli, Alma; Testai, Lara; Taglialatela, Maurizio; Calderone, Vincenzo; Ghelardini, Carla | |
| Epilepsy-causing mutations in kv7.2 c-terminus affect binding and functional modulation by calmodulin. | 1-gen-2015 | Ambrosino, Paolo; Alaimo, A; Bartollino, Silvia; Manocchio, Laura; De Maria, Michela; Mosca, Ilaria; Gomis Perez, C; Alberdi, A; Scambia, G; Lesca, G; Villarroel, A; Taglialatela, Maurizio; Soldovieri, Maria Virginia | |
| Epileptic channelopathies caused by neuronal Kv7 (KCNQ) channel dysfunction | 1-gen-2020 | Nappi, P.; Miceli, F.; Soldovieri, M. V.; Ambrosino, P.; Barrese, V.; Taglialatela, M. | |
| Epileptic encephalopathy in a patientwith a novel variant in the Kv7.2 S2 transmembrane segment: Clinical, genetic, and functional features | 1-gen-2019 | Soldovieri, M. V.; Ambrosino, P.; Mosca, I.; Miceli, F.; Franco, C.; Canzoniero, L. M. T.; Kline-Fath, B.; Cooper, E. C.; Venkatesan, C.; Taglialatela, M. | |
| Erratum to: Towards the realization of label-free biosensors through impedance spectroscopy integrated with IDES technology | 1-gen-2012 | Di Capua, R.; Barra, M.; Santoro, F.; Viggiano, D.; Ambrosino, P.; Soldovieri, M. V.; Taglialatela, M.; Cassinese, A. | |
| Expression and function of Kv7.4 channels in Rat cardiac mitochondria: possible targets for cardioprotection | 1-gen-2016 | Testai, L; Barrese, V; Soldovieri, Maria Virginia; Ambrosino, Paolo; Martelli, A; Vinciguerra, I; Miceli, F; Greenwood, I; Curtis, Mj; Breschi, Mc; Sisalli, Mj; Scorziello, A; Canduela, Mj; Grandes, P; Calderone, V; Taglialatela, Maurizio | |
| Functional Characterization of Two Variants at the Intron 6-Exon 7 Boundary of the KCNQ2 Potassium Channel Gene Causing Distinct Epileptic Phenotypes | 1-gen-2022 | Mosca, Ilaria; Rivolta, Ilaria; Labalme, Audrey; Ambrosino, Paolo; Castellotti, Barbara; Gellera, Cinzia; Granata, Tiziana; Freri, Elena; Binda, Anna; Lesca, Gaetan; Difrancesco, Jacopo C; Soldovieri, Maria Virginia; Taglialatela, Maurizio | |
| Gabapentin treatment in a patient with KCNQ2 developmental epileptic encephalopathy | 1-gen-2020 | Soldovieri, M. V.; Freri, E.; Ambrosino, P.; Rivolta, I.; Mosca, I.; Binda, A.; Murano, C.; Ragona, F.; Canafoglia, L.; Vannicola, C.; Solazzi, R.; Granata, T.; Castellotti, B.; Messina, G.; Gellera, C.; Labalme, A.; Lesca, G.; Difrancesco, J. C.; Taglialatela, M. | |
| Gain of function due to increased opening probability by two KCNQ5 pore variants causing developmental and epileptic encephalopathy | 1-gen-2022 | Nappi, Mario; Barrese, Vincenzo; Carotenuto, Lidia; Lesca, Gaetan; Labalme, Audrey; Ville, Dorothee; Smol, Thomas; Rama, Mélanie; Dieux-Coeslier, Anne; Rivier-Ringenbach, Clotilde; Soldovieri, Maria Virginia; Ambrosino, Paolo; Mosca, Ilaria; Pusch, Michael; Miceli, Francesco; Taglialatela, Maurizio |