The endocannabinoid and the endogenous opioid systems interact in the modulation of social play behavior, a highly rewarding social activity abundantly expressed in young mammals. Prolonged exposure to opioid or cannabinoid receptor agonists induces cross-tolerance or cross-sensitization to their acute behavioral effects.

Unidirectional opioid-cannabinoid cross-tolerance in the modulation of social play behavior in rats

Segatto, Marco;
2019-01-01

Abstract

The endocannabinoid and the endogenous opioid systems interact in the modulation of social play behavior, a highly rewarding social activity abundantly expressed in young mammals. Prolonged exposure to opioid or cannabinoid receptor agonists induces cross-tolerance or cross-sensitization to their acute behavioral effects.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11695/85098
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