"GC column selectivity can be continuously adapted to suit analytical needs using a flow-tuneable tandem system. Its application to the separation of complex mixtures requires a deep understanding of the theory in this area. Although a number of researchers have developed specific models, a general and exhaustive theory is still missing. In this paper we have made an implementation of pre-existing models on tandem-column assemblies operated isothermally. In particular, we have investigated the effect of column length and diameter, phase thickness and oven temperature on chromatographic parameters, such as capacity factor, selectivity, and intrinsic resolution. A new approach for the correct choice of the working temperature has been proposed. This article is protected by copyright. All rights reserved."
GC models for separation optimization in pressure-tuneable tandem capillary columns operated isothermally. Part 1: theoretical aspects
NOTARDONATO, Ivan;Pasquale Avino;RUSSO, Mario Vincenzo
2013-01-01
Abstract
"GC column selectivity can be continuously adapted to suit analytical needs using a flow-tuneable tandem system. Its application to the separation of complex mixtures requires a deep understanding of the theory in this area. Although a number of researchers have developed specific models, a general and exhaustive theory is still missing. In this paper we have made an implementation of pre-existing models on tandem-column assemblies operated isothermally. In particular, we have investigated the effect of column length and diameter, phase thickness and oven temperature on chromatographic parameters, such as capacity factor, selectivity, and intrinsic resolution. A new approach for the correct choice of the working temperature has been proposed. This article is protected by copyright. All rights reserved."I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
